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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0664
All Species:
25.45
Human Site:
Y259
Identified Species:
46.67
UniProt:
O75153
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75153
NP_056044.3
1309
146670
Y259
T
A
S
T
R
G
F
Y
L
N
Q
S
T
A
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548323
1501
166268
Y451
T
A
S
T
R
G
F
Y
L
N
Q
S
T
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW19
1315
148050
Y259
T
A
S
T
R
G
F
Y
L
N
Q
S
T
A
Y
Rat
Rattus norvegicus
XP_001080615
1352
151608
Y300
T
A
S
T
R
G
F
Y
L
N
Q
S
T
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509391
982
108607
E54
K
I
F
A
P
G
T
E
P
F
S
L
Q
V
S
Chicken
Gallus gallus
XP_415920
1293
145294
Y295
T
A
S
T
R
G
F
Y
L
N
Q
S
T
A
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0JMD0
1400
155792
Y304
T
A
S
T
R
G
F
Y
L
N
Q
S
T
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAB5
1448
160833
F348
S
A
C
S
K
G
F
F
I
N
Q
S
T
D
D
Honey Bee
Apis mellifera
XP_624898
1290
145677
F280
T
A
C
A
R
G
F
F
L
N
Q
S
T
K
E
Nematode Worm
Caenorhab. elegans
P34466
1247
139903
Y253
T
C
C
T
R
G
F
Y
V
N
N
S
Q
D
G
Sea Urchin
Strong. purpuratus
XP_001198284
1101
124381
K174
R
H
V
R
D
L
L
K
S
L
D
P
S
D
A
Poplar Tree
Populus trichocarpa
XP_002314020
1343
146561
E252
K
A
L
R
E
I
L
E
H
K
G
S
A
H
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RY84
1211
135142
T233
S
Q
K
D
P
L
A
T
F
Q
V
G
N
T
I
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.3
N.A.
94.9
89.9
N.A.
60.8
83.1
N.A.
75
N.A.
52
59.8
39.9
51.9
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
96.9
92.7
N.A.
67.2
89.3
N.A.
83.6
N.A.
69
75.7
59.5
63.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
100
N.A.
93.3
N.A.
46.6
66.6
53.3
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
100
N.A.
93.3
N.A.
80
73.3
60
6.6
Percent
Protein Identity:
27.3
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
16
0
0
8
0
0
0
0
0
8
39
8
% A
% Cys:
0
8
24
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
8
0
0
24
8
% D
% Glu:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
70
16
8
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
77
0
0
0
0
8
8
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
8
% I
% Lys:
16
0
8
0
8
0
0
8
0
8
0
0
0
8
0
% K
% Leu:
0
0
8
0
0
16
16
0
54
8
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
70
8
0
8
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
8
0
0
8
0
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
62
0
16
0
0
% Q
% Arg:
8
0
0
16
62
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
47
8
0
0
0
0
8
0
8
77
8
0
8
% S
% Thr:
62
0
0
54
0
0
8
8
0
0
0
0
62
16
0
% T
% Val:
0
0
8
0
0
0
0
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _